6. Izuna Uchiha
Izuna Uchiha was the brother of Madara Uchiha. He was very strong, like his brother. Izuna Uchiha, along with Madara Uchiha, became the first Uchiha to awaken Mangekyou Sharingan. Izuna died during his battle with Tobirama Senju, the Second Hokage of Konohagakure. Later, he passed on his eyes to Madara Uchiha.
5. Shisui Uchiha
Shisui Uchiha was exceptionally gifted. He awakened both Sharingan and Mangekyou Sharingan at a very young age. Shisui Uchiha possessed the ultimate genjutsu, Kotoamatsukami, which had the ability to control humans without even them knowing. He was a Konoha Jonin, and even a member of the ANBU. He sacrificed his life for the sake of Konohagakure.